Scientists believe free radicals contribute to the ageing process, as well as the development of a number of health problems, including heart disease and cancer. Antioxidants, such as CoEnzyme Q10 (CoQ10), can neutralize free radicals and may reduce or even help prevent some of the damage they cause.
Click image to view the clinical studies relating to CoEnzyme Q10
CoEnzyme Q10 (CoQ10) is a compound found naturally in the energy-producing center of the cell known as the mitochondria. CoQ10 is involved in making an important molecule known as adenosine triphosphate (ATP). ATP serves as the cell's major energy source and drives a number of biological processes, including muscle contraction and the production of protein. CoQ10 also works as an antioxidant.
Antioxidants are substances that scavenge free radicals, damaging compounds in the body that alter cell membranes, tamper with DNA, and even cause cell death. Free radicals occur naturally in the body, but environmental toxins (including ultraviolet light, radiation, cigarette smoking, and air pollution) can also increase the number of these damaging particles. Scientists believe free radicals contribute to the aging process, as well as the development of a number of health problems, including heart disease and cancer. Antioxidants, such as CoQ10, can neutralize free radicals and may reduce or even help prevent some of the damage they cause.
Studies included in the CoEnzyme Q10 PDF download:
The advantages of a novel CoQ10 delivery system in skin photo-protection. Am J Clin Nutr 2003;77:326-30
Coenzyme Q10 protects against oxidative stress-induced cell death and enhances the synthesis of basement membrane components in dermal and epidermal cells. Biofactors. 2009 Sep-Oct;35(5):435-41.
Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies. Int J Nanomedicine. 2011;6:611-7. Epub 2011 Mar 30.
Characterisation and Skin Distribution of Lecithin-Based Coenzyme Q10-Loaded Lipid Nanocapsules. Nanoscale Res Lett. 2010 Jul 20;5(10):1561-1569.
Q10-loaded NLC versus nanoemulsions: stability, rheology and in vitro skin permeation. Int J Pharm. 2009 Jul 30;377(1-2):207-14. Epub 2009 May 22.
Modern approach to topical treatment of aging skin. Coll Antropol. 2010 Sep;34(3):1145-53.
Treatment of CoQ(10) deficient fibroblasts with ubiquinone, CoQ analogs, and vitamin C: time- and compound-dependent effects. PLoS One. 2010 Jul 30;5(7):e11897.
The design of polymer-based nanocarriers for effective transdermal delivery. Macromol Biosci. 2010 Oct 8;10(10):1171-6. FASEB J. 2010 Oct;24(10):3733-43. Epub 2010 May 21.
Aging skin is functionally anaerobic: importance of coenzyme Q10 for anti-aging skin care. Biofactors. 2008;32(1-4):245-55.
Skin aging. Acta Dermatovenerol Alp Panonica Adriat. 2008 Jun;17(2):47-54.
Beneficial effects of pro-/antioxidant-based nutraceuticals in the skin rejuvenation techniques. Cell Mol Biol (Noisy-le-grand). 2007 Apr 15;53(1):94-101.
Effect of coenzyme Q10 on the mitochondrial function of skin fibroblasts from Parkinson patients. J Neurol Sci. 2004 May 15;220(1-2):41-8.
Lipophilic antioxidants in human sebum and aging. Free Radic Res. 2002 Apr;36(4):471-7.
Coenzyme Q10, a cutaneous antioxidant and energizer. Biofactors. 1999;9(2-4):371-8.