Praventin clinical studies on acne sufferers wishing to be acne free showed visible changes, including fewer blemishes, a reduction in the amount of redness and less oiliness. The median improvement was
44% reduction in blemishes by week 2
71 % reduction by week 4
95% reduction by week 8
Evaluating Praventin™ as a dietary supplement for the support of a healthy complexion
Forty-four participants, for whom other so called 'acne
cures' had proved ineffective, but who shared the desire to be acne free,
were enrolled in the study (23 males and 21 females). For 8 weeks the subjects
were supplemented with 200mg of Praventin™. Photographs, taken by
an independent photographer were blinded and evaluated by a dermatologist.
Subject data were collected at week 0 (baseline), which
occurred before supplementation started, as well as at weeks 2, 4, and 8.
The number of blackheads (open comedones) and non-blackheads (including
whiteheads, closed comedones, papules, pustules and nodulocystic lesions)
were counted on the forehead, left cheek, right cheek, chin, and nose. For
each subject blackheads and non-blackheads were summed over the facial regions
each week.

The
graph shows time trends of total blemishes counts for individual subjects
(in blue) with the time trend of the medians superimposed (in red).
After stopping Praventin™ supplementation at week
8 the number of blemishes started to increase, as measured by an increased
number of blemishes at week 12.
Over 76% of the participants observed visible improvements, including fewer blemishes, a reduction in the amount of redness and less oiliness.
Evaluating the effectiveness of Praventin™
in a dietary supplement regimen
Forty-two participants were enrolled in the study and divided
into 3 groups. The groups were stratified for gender and baseline acne severity.
All groups were supplemented with Praventin™ for 8 successive weeks.
Group 1 received a total amount of 25mg Praventin™ per day; Group
two received a total amount of 100mg Praventin™ per day; and Group
three received a total amount of 200mg Praventin™ per day.
Subjects had front profile photographs taken by an independent
photographer. Photographs were blinded and evaluated by a dermatologist.
Subject data were reported at week 0 (baseline) and week 8.

- New Delhi, India (Dept. Dermatology, Venerology &
Leprosy, Dr. RML Hospital)
- 1 dosage study: 200 mg Praventin, twice daily (no placebo)
- 14 subjects (4 male and 10 female) with mild to moderate acne,
15-27 years (av. 21)
- Examination and photographs at week 0, 2, 4, 8 and 12 weeks.
Interviewed on self assessment of acne, complexion and self esteem/confidence.
- Photographs and data assessed by independent dermatologist

- Effect of treatment was fair to very good in 75% of cases
- Though the new lesions appeared during the treatment,
they were
- Fewer in number
- Less inflamed
- Less erythematous (redness)
- Healed in a short time ~ 3-4 days.
- Subjects noted a 'whitening' of the skin
- No adverse effects reported
- Praventin effective on both Asian and Caucasian
skin types
- Median reduction in blemishes by 29% by week 2 and 74%
by week 12
- Greater effect on infected and inflamed lesions
- Marked reduction in skin redness
- Whitening effect of the skin reported
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